SvS
Makarem A, Appoo JJ, Boodhwani M, Guo MH, Brownlee S, Demers P, Patel HJ, Hughes GC, Dagenais F, Chu MWA, Ouzounian M, Grau JB, Bozinovski J, Pozeg Z, Tseng E, Atoui R, Jassar AS; TITAN:SvS Investigators. Patient Selection for Surgery vs Surveillance in Moderately Dilated Ascending Aorta: Insights From Treatment in Thoracic Aortic Aneurysm: Surgery versus Surveillance (TITAN:SvS), an International Prospective Trial. Ann Thorac Surg. 2025 Jul;120(1):25-32. doi.org/10.1016/j.athoracsur.2025.01.020. Epub 2025 Feb 7. PMID: 39923952.
Qiu Y, Appoo JJ, Herget E, Demers P, Tseng EE, Jassar AS, Chu MWA, Moon MC, Boodhwani M, Next Frontier in Endovascular Aortic Therapy: An anatomic analysis of feasibility of endovascular treatment of ascending thoracic aortic aneurysms, JTCVS Structural and Endovascular (2025), doi: https://doi.org/10.1016/j.xjse.2025.100056.
Dagher O, Appoo JJ, Herget E, Atoui R, Baeza C, Brinkman W, Bozinovski J, Chu MWA, Dagenais F, Demers P, Desai N, El-Hamamsy I, Estrera A, Grau JB, Hughes GC, Jassar A, Kachroo P, Lachapelle K, Ouzounian M, Patel HJ, Pozeg Z, Tseng E, Whitlock R, Guo MH, Boodhwani M. Impact of nondiameter aortic indices on surgical eligibility: Results from the Treatment in Thoracic Aortic Aneurysm: Surgery Versus Surveillance (TITAN: SvS) randomized controlled trial. J Thorac Cardiovasc Surg. 2025 Mar;169(3):857-865.e1. doi.org/10.1016/j.jtcvs.2024.04.010. Epub 2024 Apr 29. PMID: 38692478.
Guo MH, Appoo JJ, Hendry P, Masters R, Chu MWA, Ouzounian M, Dagenais F, Boodhwani M; Canadian Thoracic Aortic Collaborative. Knowledge, attitudes, and practice preferences in the surgical threshold for ascending aortic aneurysm among Canadian cardiac surgeons. J Thorac Cardiovasc Surg. 2023 Jan;165(1):17-25.e2. doi.org/10.1016/j.jtcvs.2021.01.074. Epub 2021 Feb 2. PMID: 33714570.
Guo MH, Appoo JJ, Wells GA, Chu M, Ouzounian M, Fortier J, Boodhwani M. Protocol for a randomised controlled trial for Treatment in Thoracic Aortic Aneurysm: Surgery versus Surveillance (TITAN: SvS). BMJ Open. 2021 May 26;11(5):e052070. doi.org/10.1136/bmjopen-2021-052070. PMID: 34039580; PMCID: PMC8160193.
Sundt TM. Drawing the Line on Prophylactic Aortic Replacement: Primum Non Nocere. JAMA Netw Open. 2018 Aug 3;1(4):e181289. doi.org/10.1001/jamanetworkopen.2018.1289. PMID: 30646117.
Guo MH, Appoo JJ, Saczkowski R, Smith HN, Ouzounian M, Gregory AJ, Herget EJ, Boodhwani M. Association of Mortality and Acute Aortic Events With Ascending Aortic Aneurysm: A Systematic Review and Meta-analysis. JAMA Netw Open. 2018 Aug 3;1(4):e181281. doi.org/10.1001/jamanetworkopen.2018.1281. PMID: 30646119; PMCID: PMC6324275.
Jabagi H, Wells G, Boodhwani M. COMMENCE trial (Comparing hypOtherMic teMperaturEs duriNg hemiarCh surgEry): a randomized controlled trial of mild vs moderate hypothermia on patient outcomes in aortic hemiarch surgery with anterograde cerebral perfusion. Trials. 2019 Dec 9;20(1):691. doi.org/10.1186/s13063-019-3713-9. PMID: 31815641; PMCID: PMC6902484.
Vervoort D, Boodhwani M, Chu MWA, Chung JCY, Appoo JJ, Ouzounian M. Randomized controlled trials in emergency settings: Taking a HEADSTART on acute type A aortic dissection trials. J Vasc Surg Cases Innov Tech. 2024 Mar 19;10(4):101457. doi.org/10.1016/j.jvscit.2024.101457. PMID: 39034964; PMCID: PMC11259859.
Rooprai J, Boodhwani M, Beauchesne L, Chan KL, Dennie C, Wells GA, Coutinho T. Central Hypertension in Patients With Thoracic Aortic Aneurysms: Prevalence and Association With Aneurysm Size and Growth. Am J Hypertens. 2022 Jan 5;35(1):79-86. doi.org/10.1093/ajh/hpaa183. PMID: 33759993; PMCID: PMC8730498.
Boczar KE, Boodhwani M, Beauchesne L, Dennie C, Chan KL, Wells GA, Coutinho T. Aortic Stiffness, Central Blood Pressure, and Pulsatile Arterial Load Predict Future Thoracic Aortic Aneurysm Expansion. Hypertension. 2021 Jan;77(1):126-134. doi.org/10.1161/HYPERTENSIONAHA.120.16249. Epub 2020 Nov 30. PMID: 33249858.
Rooprai J, Boodhwani M, Beauchesne L, Chan KL, Dennie C, Nagpal S, Messika-Zeitoun D, Coutinho T. Thoracic Aortic Aneurysm Growth in Bicuspid Aortic Valve Patients: Role of Aortic Stiffness and Pulsatile Hemodynamics. J Am Heart Assoc. 2019 Apr 16;8(8):e010885. doi.org/10.1161/JAHA.118.010885. PMID: 30966855; PMCID: PMC6507195.
Boczar KE, Cheung K, Boodhwani M, Beauchesne L, Dennie C, Nagpal S, Chan K, Coutinho T. Sex Differences in Thoracic Aortic Aneurysm Growth. Hypertension. 2019 Jan;73(1):190-196. doi.org/10.1161/HYPERTENSIONAHA.118.11851. PMID: 30571545.
Jue J, Boodhwani M, Beauchesne L, Dennie C, Nagpal S, Chan KL, Coutinho T. Greater Aortic Stiffness and Pulsatile Arterial Load Are Associated With Larger Thoracic Aortic Aneurysm Size in Women. Circulation. 2019 Feb 19;139(8):1124-1126. doi.org/10.1161/CIRCULATIONAHA.118.037630. PMID: 30779642.